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Results for "

antiprotozoal activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (7) Apoptosis (1) Bacterial (11) Drug Metabolite (1) Fungal (4) Isotope-Labeled Compounds (2) Lactate Dehydrogenase (2) Parasite (22) Reactive Oxygen Species (3)
By Research Areas:	Cancer (4) Infection (23) Inflammation/Immunology (4) Metabolic Disease (1)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147857

Antileishmanial agent-12	Parasite	Infection
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC₅₀ values of 14.9, 21.3 and 9.3 μM, respectively .

HY-147856

Antileishmanial agent-11	Parasite	Infection
Antileishmanial agent-11 (compound 4d) is a potent anti-leishmanial agent. Antileishmanial agent-11 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC₅₀ values of 28.3, 24.8 and 13.0 μM, respectively .

HY-B0226A

(E)-Nitrofurazone (E)-Nitrofural	Bacterial Parasite	Infection
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .

HY-N6587

Betulinic acid methyl ester

Methyl betulinate
Parasite Others

Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .

Betulinic acid methyl ester Methyl betulinate	Parasite	Others
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .

HY-N10255

Trypacidin	Parasite	Infection
Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process .

HY-B1336

Furazolidone 2 Publications Verification	Bacterial Apoptosis Antibiotic Parasite	Infection Cancer
Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.

HY-P5696

Xenopsin precursor fragment	Bacterial Parasite Fungal	Infection
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .

HY-N11173

cis-Melilotoside	Others	Metabolic Disease
cis-Melilotoside, an o-Coumaric acid derivative, shows potent antioxidant activity. cis-Melilotoside has antiprotozoal activity moderately against T. cruzi with an IC₅₀ of 78.2 ug/mL .

HY-17008

Toltrazuril (sulfone) Ponazuril	Parasite	Infection
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry .

HY-115249

Metronidazole acetic acid	Bacterial Parasite Antibiotic	Infection
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and *protozoa* .

HY-N0914

Ajugol 1 Publications Verification	Parasite	Others
Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC₅₀ of 31.8 μg/mL .

HY-W040073

Nifurtimox	Parasite Lactate Dehydrogenase	Infection Cancer
Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

HY-101848

Latrunculin B	Fungal	Infection
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .

HY-G0016

N-Acetyl dapsone MADDS; Monoacetyldapsone	Drug Metabolite	Others
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .

HY-N7632

5-Desmethylsinensetin	Bacterial	Infection Inflammation/Immunology
5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC₅₀ values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively .

HY-W040073S

Nifurtimox-d4	Isotope-Labeled Compounds Parasite Lactate Dehydrogenase	Infection Cancer
Nifurtimox-d₄ is deuterium labeled Nifurtimox. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

HY-B0295

Chloroxine 1 Publications Verification	Bacterial Antibiotic Parasite	Infection
Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .

HY-N9179

3′,4′,5′,5,6,7-Hexamethoxyflavone	Parasite	Infection
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC₅₀ of 21.3 μM (8.58 g/mL) .

HY-N7516

4'-Hydroxy-2,4-dimethoxychalcone	Parasite Bacterial Fungal	Infection
4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity .

HY-N10547

6-O-Methylcatalpol	Parasite	Infection
6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC₅₀: 32.5 and 8.3 μg/mL) .

HY-147766

Antileishmanial agent-10

Parasite Infection

Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent .

Antileishmanial agent-10	Parasite	Infection
Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent .

HY-P2450

Leucinostatin A Antibiotic P168	Fungal Antibiotic	Infection Cancer
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

HY-B0688

Dapsone 4,4′-Diaminodiphenyl sulfone; DDS	Antibiotic Parasite Bacterial Reactive Oxygen Species	Infection Inflammation/Immunology
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-146487

Anti-infective agent 1	Bacterial Parasite	Infection
Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .

HY-155281

Antiparasitic agent-18	Parasite	Infection
Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC₅₀=0.4 μM), T. cruzi (EC₅₀=0.21 μM), and L. donovani (EC₅₀=0.26 μM). Antiparasitic agent-18 has potent *antiprotozoal* activity .

HY-B0688S1

Dapsone-d4 4,4′-Diaminodiphenyl sulfone-d₄; DDS-d₄	Antibiotic Parasite Bacterial Reactive Oxygen Species	Infection Inflammation/Immunology
Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].

HY-B0688S2

Dapsone-13C12 4,4′-Diaminodiphenyl sulfone-¹³C₁₂; DDS-¹³C₁₂	Isotope-Labeled Compounds Antibiotic Parasite Bacterial Reactive Oxygen Species	Infection Inflammation/Immunology
Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

Xenopsin precursor fragment	Bacterial Parasite Fungal	Infection
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0914

Ajugol 1 Publications Verification	Structural Classification Iridoids Classification of Application Fields Terpenoids Labiatae Source classification Other Diseases Scrophulariaceae Lactuca perennis Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Disease Research Fields	Parasite
Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC₅₀ of 31.8 μg/mL .

HY-101848

Latrunculin B	Infection Animals Classification of Application Fields Marine natural products Sponge Disease Research Fields	Fungal
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .

HY-N6587

Betulinic acid methyl ester Methyl betulinate	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Parasite
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .

HY-N10255

Trypacidin	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite
Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process .

HY-N11173

cis-Melilotoside	Structural Classification Simple Phenylpropanols Orchidaceae Source classification Phenylpropanoids Plants Dendrobium chryseum Z. H. Tsi et S. C. Chen	Others
cis-Melilotoside, an o-Coumaric acid derivative, shows potent antioxidant activity. cis-Melilotoside has antiprotozoal activity moderately against T. cruzi with an IC₅₀ of 78.2 ug/mL .

HY-N7632

5-Desmethylsinensetin	Classification of Application Fields Flavones Source classification Plants Compositae Infection Monophenols Flavonoids other families Erythrina eriotriocha Phenols Inflammation/Immunology Disease Research Fields	Bacterial
5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC₅₀ values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively .

HY-N9179

3′,4′,5′,5,6,7-Hexamethoxyflavone	Infection Flavonoids Classification of Application Fields Flavones Source classification Lupinus perennis L. Plants Compositae Disease Research Fields	Parasite
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC₅₀ of 21.3 μM (8.58 g/mL) .

HY-N7516

4'-Hydroxy-2,4-dimethoxychalcone	Infection Flavonoids Chalcones Monophenols Classification of Application Fields Source classification Phenols Plants Umbelliferae Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Parasite Bacterial Fungal
4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity .

HY-N10547

6-O-Methylcatalpol	Structural Classification Scrophularia ningpoensis Hemsl. Polymer products Scrophulariaceae Plants Saccharides Monosaccharides	Parasite
6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC₅₀: 32.5 and 8.3 μg/mL) .

HY-P2450

Leucinostatin A Antibiotic P168	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Fungal Antibiotic
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

Cat. No.	Product Name	Chemical Structure

HY-W040073S

Nifurtimox-d4
Nifurtimox-d₄ is deuterium labeled Nifurtimox. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

HY-B0688S1

Dapsone-d4
Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].

HY-B0688S2

Dapsone-13C12
Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

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